S3E Engineers has over 20 years of experience designing laboratory facilities for the National Institutes of Health, Food and Drug Administration, and other federal and county government clients. Most projects required sophisticated environmental controls to maintain space pressure and precise temperature and humidity conditions. Many projects were in existing buildings that had to remain in operation while the construction work took place, requiring close coordination with laboratory engineering and research staffs to assure a successful outcome with a minimum of disruption to laboratory operations.

S3E Engineers has designed many of the major types of laboratories and vivarium facilities encountered in medical research as well as testing laboratories for county health departments and sewer and water treatment facilities. A partial listing of these types of laboratories is listed below:

  • Bio-safety Level 2 (BSL-2) and 3 (BSL-3) medical research laboratories
  • BSL-2 and BSL-3 vivariums
  • Electron microscope laboratories
  • Surgical pathology laboratories
  • NMR and Mass Spectrometry laboratories
  • Cryogenic Cold Rooms
  • Clean rooms for formulating reagent water
  • Analytical Chemistry & Immunology Laboratories
  • Water and sewage treatment plant laboratories
  • County health department laboratories

National Institutes of Health (NIH)
Bethesda, MD

  • Building 10 National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 50 Module Laboratory Renovation
  • Building 8A NMR and Mass Spectrometry Laboratory
  • Building 49 Transgenic Mouse Laboratory Renovation
  • Avian Flu Research Laboratories
  • Cryogenic Cold Rooms
  • Maus Haus Vivarium and Necropsy suite renovation.

Georgetown University
Washington, DC

  • Pre-Clinical Science Laboratory Renovation
  • Med-Dent Laboratory Renovation

Food and Drug Administration
Beltsville, Maryland

  • Module 1 – 250,000 SF Laboratory
  • Center for Veterinary Medicine Module 2 $39,000,000 New Laboratory and Animal Holding Facility
  • Clean Steam and Reverse Osmosis System Design Module 1

Southern Research Institute
Frederick, Maryland

  • Bio-Safety Level 2 Laboratory Renovation
  • Bio-Safety Level 3 Renovation & Central Plant Addition
  • JVAP Containment Laboratory Renovation

University of Virginia Medical Center
Charlottesville, Virginia

  • Genomics Laboratory Renovation
  • Electrophysiology Laboratory Renovation

Cellular Laboratory Renovation
Surgical Pathology Laboratory Renovation

  • Electron Microscope Laboratory Renovation
  • Surgical Pathology Laboratory Renovation

TherImmune Research Corporation
Gaithersburg, Maryland

  • 28 Room Vivarium and Support Spaces
  • Analytical Chemistry & Immunology Laboratory

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Case Studies