S3E Engineers has over 20 years of experience designing laboratory facilities for the National Institutes of Health, Food and Drug Administration, and other federal and county government clients. Most projects required sophisticated environmental controls to maintain space pressure and precise temperature and humidity conditions. Many projects were in existing buildings that had to remain in operation while the construction work took place, requiring close coordination with laboratory engineering and research staffs to assure a successful outcome with a minimum of disruption to laboratory operations.
S3E Engineers has designed many of the major types of laboratories and vivarium facilities encountered in medical research as well as testing laboratories for county health departments and sewer and water treatment facilities. A partial listing of these types of laboratories is listed below:
- Bio-safety Level 2 (BSL-2) and 3 (BSL-3) medical research laboratories
- BSL-2 and BSL-3 vivariums
- Electron microscope laboratories
- Surgical pathology laboratories
- NMR and Mass Spectrometry laboratories
- Cryogenic Cold Rooms
- Clean rooms for formulating reagent water
- Analytical Chemistry & Immunology Laboratories
- Water and sewage treatment plant laboratories
- County health department laboratories
National Institutes of Health (NIH)
- Building 10 National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 50 Module Laboratory Renovation
- Building 8A NMR and Mass Spectrometry Laboratory
- Building 49 Transgenic Mouse Laboratory Renovation
- Avian Flu Research Laboratories
- Cryogenic Cold Rooms
- Maus Haus Vivarium and Necropsy suite renovation.
- Pre-Clinical Science Laboratory Renovation
- Med-Dent Laboratory Renovation
Food and Drug Administration
- Module 1 – 250,000 SF Laboratory
- Center for Veterinary Medicine Module 2 $39,000,000 New Laboratory and Animal Holding Facility
- Clean Steam and Reverse Osmosis System Design Module 1
Southern Research Institute
- Bio-Safety Level 2 Laboratory Renovation
- Bio-Safety Level 3 Renovation & Central Plant Addition
- JVAP Containment Laboratory Renovation
University of Virginia Medical Center
- Genomics Laboratory Renovation
- Electrophysiology Laboratory Renovation
Cellular Laboratory Renovation
Surgical Pathology Laboratory Renovation
- Electron Microscope Laboratory Renovation
- Surgical Pathology Laboratory Renovation
TherImmune Research Corporation
- 28 Room Vivarium and Support Spaces
- Analytical Chemistry & Immunology Laboratory
Fairfax County Health Department Laboratory
A former school building was converted into biosafety level 2 and 3 laboratories and administrative office space for the Fairfax County Health Department. The design included chemical fume hoods, biosafety cabinets, snorkel exhaust, and various laboratory equipment. The HVAC system includes a custom rooftop unit with energy recovery and redundant fans and HEPA filtration of the BSL-3 suite exhaust. This project has been awarded the Associated Builders and Contractors 2010 Metropolitan Washington Excellence in Construction Award.
Noman Cole Pollution Control Plant Laboratory Upgrades
After a feasibility study was performed to establish the project scope, the following renovations were made to the laboratory used to support the wastewater treatment facility. The project was phased to allow the facility to remain operational during the renovations.
- Decrease energy use by providing a new HVAC system for the administrative areas.
- Provide additional exhaust snorkels and equipment exhaust hoods.
- Troubleshoot and repair the existing pneumatic laboratory exhaust controls.
- Replace the existing HVAC direct digital control (DDC) system.
- Replace the HVAC humidifier with a different type that was easier to maintain.
- Commission the entire HVAC system.
NIH Building 8A Electron Microscope Suite
The microscope rooms were designed to very precise vibration, temperature, acoustic, and humidity requirements. A regenerative desiccant system was used to maintain the humidity between 15% – 20% RH and room temperature between 68 – 72 degrees F.